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Staying with IVF may be best for low responders.(NEWS)(in vitro fertilization )(Report)

OB GYN News

| January 01, 2009 | Worcester, Sharon | COPYRIGHT 2009 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SAN FRANCISCO -- The likelihood of a clinical pregnancy in patients who were converted from in vitro fertilization to intrauterine insemination because of low response was just 5% in a retrospective review of 362 patients.

These results suggest that proceeding with IVF may still be best for some patients, said Dr. John M. Norian of the National Institute of Child Health and Human Development.

The findings, presented at the annual meeting of the American Society for Reproductive Medicine, were based on a review of 12,609 IVF patients and 6,664 IUI patients from Shady Grove Fertility Center, a large private fertility center based in Rockville, Md. The 362 patients evaluated included those from the database who were having a first IVF-to-IUI conversion cycle, and who had at least one patent fallopian tube and an insemination total motile sperm count of at least 5 million.

Low response in this retrospective study was defined as fewer than four oocytes expected at retrieval and a low serum estradiol level.

Besides the 362 who met the inclusion criteria, 407 ...

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