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Washington -- Women with a history of preeclampsia or eclampsia had more than twice the risk of developing cardiovascular disease than that of women with uncomplicated pregnancies, based on results of a meta-analysis that included more than 100,000 preeclamptic women.
Results from previous studies have shown associations between preeclampsia and increased risk of stroke and hypertension later in life.
To evaluate the long-term risk for cardiovascular problems in women with preeclampsia or eclampsia (referred to as PET), Dr. Sarah McDonald and her colleagues at Mc-Master University Hamilton, Ont., conducted a meta-analysis of 5 case-control studies and 10 cohort studies. The studies included data from 118,990 preeclamptic women and 2.3 million women without PET.
The selected studies examined the development of cardiovascular disease or mortality at more than 6 weeks post partum in women with and without PET. Most (11 of 15) studies focused on women aged younger than 56 years.
The results were presented in a poster at the annual congress of the International Society for the Study of ...