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Increasingly, the clinical cancer research community is recognizing the importance of unique issues associated with long-term survival following successful treatment of a malignancy. It has been well known for many years that late effects of cancer treatment--such as the development of secondary cancers and heart failure--may result in a devastating outcome.
Investigators have begun to focus, however, on concerns that have a far greater potential impact on the individual patient's overall quality of life than on the duration of survival. Examples of such issues include platinum- or taxane-induced peripheral neuropathy and chemotherapy-associated chronic fatigue that may persist long after the completion of the treatment program.
A report at the annual meeting of the European Society for Therapeutic Radiology and Oncology highlights such concerns specifically in the area of gynecologic cancers. The results of a survey, conducted among a group of 677 women who received radiotherapy for a gynecologic malignancy in Sweden from 1991 to 2003, revealed that "unexpected defecation in clothing" was reported in as many as 10% of respondents. This striking and clearly disturbing result focuses not only on the particular serious issue, but also reveals another problem: the uncertain willingness of cancer patients to report to their health providers what can only be described as very personal and embarrassing concerns.
Recognizing that these women are almost certainly quite happy to be alive (to become a "cancer survivor"), are grateful for the care they have received, and are not particularly interested in being seen as a "complainer" (particularly if it is believed there is little that can be done regarding the problem), it is reasonable to argue that such individuals might remain largely silent about these matters. As a result, the oncology community, both clinicians and researchers, may be quite unaware of the magnitude of this and similar issues--for example, sexual dysfunction.
A patient may ...
Source: HighBeam Research, Watch for long-term issues after gyn. cancer.(EDITORIAL)