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ORLANDO, FLA. -- Fish consumption, especially of tuna and other dark-meat fish, is associated with significantly decreased angiographic progression of coronary artery disease in postmenopausal women, Arja T. Erkkila, Ph.D., reported at the annual scientific sessions of the American Heart Association.
Serial angiography suggests this effect is most pronounced in diabetic postmenopausal women, a population at particularly high risk of coronary events, added Dr. Erkkila of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University Boston.
She presented a secondary analysis of data from the Estrogen Replacement and Atherosclerosis (ERA) trial involving 226 postmenopausal women with known coronary artery disease who underwent quantitative coronary angiography at baseline and again after a mean 3.2 years of follow-up. The women also completed a detailed food frequency questionnaire at baseline.
Fish intake was the subject of this study because while the AHA currently recommends eating fish at least twice per week on the basis of studies linking this practice to reduced cardiovascular morbidity and mortality, these supporting studies primarily involved men. And there have been no prior studies at all relating fish intake to angiographic measurement of coronary luminal narrowing in postmenopausal women with established coronary disease, according to Dr. Erkkila.
Roughly one-third of the ERA participants ate fish at least twice weekly. Their rate of ...