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Congenital heart defects linked to rise in small for gestational age infants: study of almost 5,000 infants.(Obstetrics)
ORLANDO, FLA. -- Infants with congenital heart defects are more likely to be small for gestational age than those born with a normal heart, Dr. Sadia Ghaffar said at the annual scientific sessions of the American Heart Association.
They are also more prone to asymmetric intrauterine growth, according to Dr. Ghaffar, a pediatric cardiologist at Arkansas Children's Hospital, Little Rock.
She reported on a case-control study involving nearly 5,000 infants enrolled in the National Birth Defects Prevention Study, an ongoing multicenter study that is the largest-ever investigation of birth defects in the United States. Her analysis compared the characteristics of 2,550 infants born with congenital heart defects to the characteristics of 2,352 controls.
The mean birth weight of babies with congenital heart defects was 2,985 g, significantly less than the mean birth weight of 3,376 g in controls.
Small for gestational age was diagnosed in 18.4% of infants with congenital heart defects, compared with 8.3% of controls. After controlling for potential confounding maternal and infant characteristics, infants with an isolated congenital heart defect had ...
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