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High-dose tamoxifen for IVF in breast cancer survivors: combine with FSH.(Gynecology)
SAN ANTONIO -- High-dose tamoxifen cari do double duty when used during in vitro fertilization cycles for breast cancer patients and survivors.
Moreover, the addition of follicle stimulating hormone (FSH) can increase the number of embryos obtained during in vitro fertilization (IVF), Dr. Kutluk Oktay said at the annual meeting of the American Society for Reproductive Medicine.
"Tamoxifen has a dual purpose in simultaneously protecting the breast while also stimulating the ovaries. But the [average] number of embryos we can get with just tamoxifen alone is still less than two. If we combine the tamoxifen with FSH, we can double the number of embryos," said Dr. Oktay of Cornell University, New York.
Standard ovarian stimulation protocols for IVF are potentially risky in the context of breast cancer because of the possibility that high estrogen levels could trigger a recurrence of the disease.
Traditionally, natural IVF--in which the ovaries are not artificially stimulated--has been the only safe option for these patients, yielding low numbers of embryos.
More recently, Dr. Oktay and his associates have published data on 12 breast cancer patients who underwent IVF involving high-dose tamoxifen (40-60 mg for an average of 6.9 days beginning ...
- Letrozole, low-dose FSH lead to IVF pregnancy.(Gynecology)
- Magazine article from: OB GYN News Johnson, Kate December 1, 2004 700+ words
...addition, one patient in the letrozole/FSH group became pregnant after transfer...inhibitors used in the treatment of breast cancer, work differently when it comes to...see enough estrogen it makes more FSH to stimulate the ovaries," he said...
- FSH blood test.(Follicle stimulating hormone)
- Clinical Reference Systems Richards, Tom January 1, 2006 700+ words
What is the FSH blood test? The FSH test measures the level of follicle stimulating hormone (FSH) in your blood. This hormone is produced by a gland in your brain. In women FSH stimulates the production of eggs and is important in the regulation...
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- Press release article from: M2 Presswire November 10, 2009 700+ words
...Research and Markets: Competitor Analysis: FSH, hCG and LH - Therapeutic Proteins for...addition of the "Competitor Analysis: FSH, hCG and LH - Therapeutic Proteins for...offering. The Competitive Intelligence Report FSH, hCG and LH: Therapeutic Proteins for...
- Research and Markets: Competitor Analysis: FSH, hCG and LH - Therapeutic...
- Press release article from: Business Wire November 10, 2009 700+ words
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- Vitro Diagnostics, Inc. Awarded Patent for FSH Purification Technology.
- Press release article from: PR Newswire November 30, 1999 700+ words
...for its patent entitled "Method for Purifying FSH." This patent claims an improved method for the purification of FSH, which is a pituitary hormone important in the regulation of reproduction. FSH is also used as a fertility drug with a current...
- Research and Markets Adds Report: Competitor Analysis: FSH, hCG and LH.
- Magazine article from: Health & Beauty Close-Up November 12, 2009 700+ words
...addition of the "Competitor Analysis: FSH, hCG and LH - Therapeutic Proteins for...include: The Competitive Intelligence Report FSH, hCG and LH: Therapeutic Proteins for...novel recombinant, transgenic and oral FSH, hCG and LH receptor agonists for treatment...
- A Valuable Competitor Analysis Report on Follicle Stimulating Hormones (FSH):...
- Press release article from: M2 Presswire November 7, 2008 700+ words
...Report on Follicle Stimulating Hormones (FSH): With a Focus on the Market Size, Preparations...Analysis: Follicle Stimulating Hormone (FSH)" report to their offering. This Competitive...report on Follicle-Stimulating Hormones (FSH) provides a competitor analysis report...
- Tracking FSH annually said to help predict bone loss in...
- Magazine article from: OB GYN News Moon, Mary Ann March 1, 2006 700+ words
...found that the interaction between the baseline FSH level obtained before menopause and serial FSH levels taken every year thereafter predicted bone...interaction "is complex, requires at least two FSH values, and may be challenging to apply in a...
Source: HighBeam Research, High-dose tamoxifen for IVF in breast cancer survivors: combine with...