|
COPYRIGHT 2003 International Medical News Group
CHICAGO -- When diagnosing a collagenolytic granuloma, take your cues from color.
Biopsies of these lesions will show areas of altered collagen and will stain either blue or red. Mucin and neutrophils or nuclear dust will stain blue; fibrin, hyalinized collagen, and eosinophils will stain red.
"These color distinctions allow a simple approach to differential diagnosis," Dr. Terry L. Barrett said at the annual meeting of the American Society of Dermatopathology.
Blue Collagenolytic Granulomas
Blue-staining granulomas contain neutrophils and nuclear dust or interstitial mucin. If mucin is present and confirmed by an Alcian blue or colloidal iron stain, the diagnosis is likely to be granuloma annulare. If the blue color is due to the presence of neutrophils or nuclear dust, the granuloma is either Wegener's granulomatosis or rheumatoid vasculitis, said Dr. Barrett of the department of dermatology at Johns...
Read the full article for free courtesy of your local library.
|
Bookmark this article
Print this article
Link to this article
Email this article
Digg It!
Add to del.icio.us
RSS
