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C-reactive protein elevation linked to gestational diabetes: early pregnancy.(Obstetrics)
ATLANTA -- Elevations in maternal C-reactive protein during early pregnancy are associated with an increased risk for gestational diabetes, Dr. Chun-Fang Qiu said at the annual meeting of the Society for Pediatric and Perinatal Epidemiologic Research.
In a prospective cohort study that enrolled 851 women, those whose C-reactive protein (CRP) concentrations were in the highest tertile by 16 weeks' gestation had a 5.2-fold increased risk of developing gestational diabetes, compared with those in the lowest tertile. (See chart.)
Elevations in acute phase proteins indicating subacute inflammation have previously been reported in association with type 2 diabetes. There is a relatively large body of literature documenting positive associations of CRP with insulin resistance, hyperglycemia, and glucose intolerance, said Dr. Qiu of Swedish Medical Center, Seattle. Little attention has been paid to the potential ...
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Screening for gestational diabetes is commonly recommended despite...of a common definition of gestational diabetes. Furthermore, there is...subject and concludes that gestational diabetes is simply impaired glucose...
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Source: HighBeam Research, C-reactive protein elevation linked to gestational diabetes: early...