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WASHINGTON -- Babies delivered by planned cesarean section are significantly more likely to require hospitalization for asthma during childhood than babies born vaginally, Dr. Gordon Smith reported at the annual meeting of the Society for Gynecologic Investigation.
The association between planned cesarean section and childhood asthma hospitalizations was strongest for infants who developed neonatal respiratory complications after birth; these children had a 75%-80% increase in the risk of hospital admissions for asthma over the first 5 years of life, according to Dr. Smith.
"We've known for a long time that there is an association between cesarean section and short-term respiratory morbidity; but we really didn't think that was reflected in increased risks over the long term," Dr. Smith of Cambridge (England) University, said in an interview.
"Apparently, however, it is," he added.
He believes the increased incidence of asthma among these children is related to an inflammatory process in the lungs at the time of birth, which leads to conditioning of bronchial smooth muscle toward a hyperresponsive, proinflammatory phenotype.
Dr. Smith's retrospective cohort study ...
Source: HighBeam Research, Asthma associated with planned cesarean. (Large Retrospective Study).