Toradol cult narcotics, pain after cesareans. (Double-Blind, Randomized Study).

ANAHEIM, CALIF. -- Post-operative pain and narcotic use were significantly reduced in patients who received ketorolac tromethamine following cesarean section in a placebo-controlled, double-blind randomized study.

Starting 1 hour after administration and continuing through 24 hours, 23 patients receiving the nonsteroidal anti-inflammatory drug rated their pain at least one digit lower on a 0-10 visual analogue scale than did 22 patients receiving placebo, Dr. Jerry Lowder said at the annual meeting of the Society of Gynecologic Surgeons.

Additionally, they used a total of 28 mg of morphine from patient-controlled analgesic pumps, compared with the 42 mg used by patients who received placebo. Ketorolac tromethamine patients attempted to get more morphine 40 times during the 24-hour study period; patients receiving placebo pushed the button an average of 60 times.

Because the drug, marketed as Toradol, carries a black box warning against its use in labor and delivery, an investigational new drug application was filed and approved by the Food and Drug Administration before the study began.

Ketorolac tromethamine is widely used in gynecologic and other forms of ...