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COPYRIGHT 2007 International Medical News Group
AMSTERDAM -- Data from an international trial have yielded a formula that accurately converts hemoglobin [A.sub.1c] values to an estimated average blood glucose level.
The results of the [A.sub.1c]-Derived Average Glucose (ADAG) study, which included 4 months' worth of glucose data from 643 diabetic and nondiabetic subjects from 10 centers around the world, provided this "simple, linear" equation to obtain glucose values in mmol/L: (1.583 X Hb[A.sub.1c]) - 2.52. Thus, when multiplied by 18 to get the value in the American units mg/dL, a hemoglobin [A.sub.1c] of 6% is converted to approximately 126 mg/dL, 7% is converted to 155 mg/dL, and 8% is converted to 182 mg/dL.
"The results are even better than we expected or could have hoped for. There's a linear correlation between the Hb[A.sub.1c] and the calculated mean glucose over a wide range of [A.sub.1c] values.... The results should apply to the majority of patients with diabetes," study...
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