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SAN FRANCISCO -- Results of the first case-control study of third-trimester amniocentesis suggest the procedure is not associated with an increased risk of obstetric problems within 48 hours of testing.
Findings of the 220-patient study are supported by previous data derived from case series suggesting that the immediate risks of third-trimester amniocentesis are minimal, Dr. Catherine Y. Spong said in a poster presentation at the annual meeting of the Society for Maternal-Fetal Medicine.
"Pooling the published data and including ours, stillbirth or neonatal death after third-trimester amniocentesis has never been reported among 1,919 cases," said Dr. Spong of Georgetown University, Washington. Less dear is whether third-trimester amniocentesis might increase the risk for obstetric complications. In two recent case series with 1,500 third-trimester amniocenteses, nearly 1% of cases required an emergency cesarean section due to fetal or ...