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CHICAGO -- Postmenopausal women who ate a 2-ounce bag of soy nuts a day had a significant reduction in their blood pressure in a controlled pilot study.
"The effect on blood pressure was somewhat unexpected. The reduction was comparable to what's achieved by some antihypertensive medications," Dr. Francine K. Welty said at the annual scientific sessions of the American Heart Association.
Statistically and clinically significant blood pressure reductions were seen in both normotensive women and those who were hypertensive, said Dr. Welty, director of cardiovascular care for women at Beth Israel Deaconess Medical Center in Boston. The next step is to try to confirm these results in a larger and longer-term study she said.
The crossover study involved 61 postmenopausal women, 49 of whom were normotensive, and 12 with hypertension, defined as an entry systolic blood pressure of at least 140 mm Hg and a diastolic pressure of at least 90 mm Hg. The average age of the women in the normotensive group was 53.5 years, compared with 58.3 years in the hypertensive group.
The women first went through a 4-week run-in period, during which they received dietary counseling aimed at controlling their daily intake of total and saturated fat and eating at least two fatty fish meals a week. At the end of the run-in, blood pressure and serum cholesterol levels were measured, and the women were then randomized to either ongoing dietary counseling, or counseling plus a daily 58-g serving of dry roasted soy nuts.
Each day's supply of nuts delivered 240 calories, 25 g of soy protein, and 101 mg of active-form isoflavones. The women who were assigned to eat the soy nuts bad ...