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Radiation beneficial in elderly patients after breast-conserving Tx. (Large Retrospective Review).
SAN ANTONIO -- Omitting radiation therapy following breast-conserving surgery in elderly patients adversely affects survival, Dr. Pauline T. Truong said at a breast cancer symposium sponsored by the San Antonio Cancer Institute.
Dr. Truong of the British Columbia Cancer Agency in Vancouver conducted a retrospective review of 5,557 women aged 50-89 followed for a median of 6.4 years after undergoing breast-conserving surgery for invasive breast cancer. Her purpose was to learn whether radiotherapy after breast-conserving surgery was beneficial in patients older than 75, a group that hasn't been adequately represented in the major clinical trials.
Radiotherapy is commonly omitted from the breast-conserving therapy regimen in patients of advanced age. Many physicians don't want to subject these women to the rigors of added treatment, particularly in the absence of evidence of substantial benefit. Such was the case in this large Canadian patient series, where nearly 32% of women above 75 years didn't receive radiotherapy following breast-conserving surgery, compared with 13%-14% of patients aged 50-75.
Tumor characteristics were closely similar in elderly women ...
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- News wire article from: The America's Intelligence Wire October 6, 2005 700+ words
...include a combination of breast-conserving surgery and radiation therapy. In the past, the only treatment for breast cancer was the removal of the entire...the less-radical breast-conserving surgery (lumpectomy) followed by radiation...
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...treatment for early breast cancer in women who want...removal. Breast-conserving surgery (BCS), as it is...women with early breast cancer were treated with...analysis singled out the breast cancer patients whose odds...
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- Press release article from: PR Newswire March 12, 2004 700+ words
...years, breast conserving surgery has been the...early stage breast cancer. However...of breast conserving surgery done in the...early stage breast cancer involving...undergo breast conserving surgery. Members...
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- Magazine article from: Health Services Research Brooks, John M. Chrischilles, Elizabeth A. Scott, Shane D. Chen-Hardee, Shari S. December 1, 2003 700+ words
...for patients with early stage breast cancer (stages I, IIa, and IIb...mastectomy (MAS) or breast conserving surgery plus irradiation (BCSI...most women with early stage breast cancer (ESBC) based on randomized...
- Radiotherapy improves survival after early stage, breast-conserving surgery.
- Newspaper article from: Biotech Business Week February 9, 2004 700+ words
...breast-conserving surgery for early-stage breast cancer is associated...early-stage breast cancer who have breast-conserving surgery followed...early-stage breast cancer who underwent breast-conserving surgery alone or...
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- News wire article from: Asia Africa Intelligence Wire October 28, 2005 700+ words
...the topic of "Breast Conserving Surgery- A New Concept in Pakistan...years with early stage breast cancer who had breast-conserving surgery. This will also convince...poster in 4th "Future of Breast Cancer" conference held at Bermuda...
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- Newspaper article from: Cancer Weekly April 6, 2004 700+ words
...breast-conserving surgery has been the...early stage breast cancer. However...of breast-conserving surgery done in the...early stage breast cancer involving...undergo breast-conserving surgery. Members...
- 10-year survival study shows breast conserving surgery plus irradiation equal...
- Newspaper article from: Cancer Weekly December 16, 1991 700+ words
...up studies to be reported on breast conserving surgery in women with intraductal breast cancer shows a cases-specific survival of...survival rate (including deaths only from breast cancer) was 97 percent. There were 28 failures...
- More data support breast-conserving surgery. (Phase I or II Cancer).
- Magazine article from: OB GYN News Norton, Patrice G.W. January 15, 2003 700+ words
...women treated with breast-conserving surgery and radiation developed an ipsilateral in-breast cancer event. Survival at Specified...83% 73% 71% 69% Breast-conserving surgery plus radiation 81% 76% 70...
- Breast-conserving surgery and definitive radiation: a comparison between...
- Newspaper article from: Cancer Weekly Fagundes, M.A. Fagundes, H.M. Brito, C.S. Fagundes, M.H. Bruno, L.A. Azevedo, S.J. Fagundes, L.A. November 9, 1992 700+ words
...California, "Breast-conserving surgery and definitive radiation...mastectomy for early stage breast cancer is a well-accepted practice...patients with stages I and II breast cancer underwent conservative surgery...patients with stages I and II breast cancer treated with ...
Source: HighBeam Research, Radiation beneficial in elderly patients after breast-conserving Tx....