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Intramedullary spinal cord metastasis marks the end of disease course.

Clinical Oncology Week

| March 17, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 MAR 17 - (NewsRx.com & NewsRx.net) -- Intramedullary spinal cord metastasis marks the end of disease course.

"Intramedullary spinal cord metastases (ISCM) are usually the result of rapidly progressing systemic malignancy. Breast cancer is one of the most common solid tumors with a high propensity of CNS dissemination. In the present report we describe two new cases with advanced breast cancer developing ISCM after a variable disease course," researchers in Greece report.

"One of these patients had brain metastasis at presentation, and while in relapse developed leptomeningeal carcinomatosis which was treated successfully; but it was followed shortly, as a terminal event, by ISCM and parenchymal brain recurrence. The other patient was treated initially for locally advanced breast cancer and after multiple locoregional relapses, she developed liver metastasis, and subsequent ISCM and asymptomatic parenchymal brain deposits. Both patients experienced a rather rapidly evolving disease course leading to death at 2 and 4 months, respectively, after the widespread neuraxis dissemination of their cancer," wrote C. Kosmas and colleagues, Helena Venizelou Hospital.

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Source: HighBeam Research, Intramedullary spinal cord metastasis marks the end of disease course.

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