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SEOUL, Nov 1 Asia Pulse - South Korean researchers on Thursday announced the discovery of a new substance for the treatment of diabetes that is more effective and has less side effects than existing drugs.
The team led by Ahn Jin-hee, a researcher at the state-run Korea Research Institute of Chemical Technology (KRICT), said KR66223 has shown to be about 20 times more effective in laboratory tests than the Januvia drug marketed worldwide by Merck.
The material developed with support from the Ministry of Science and Technology, strengthens the body's natural blood sugar level control system by inhibiting the negative effects of dipeptidyl peptidase IV (DPP-IV) in the stomach.
In a healthy person, the body releases the so-called incretin hormones that trigger the excretion of insulin and control blood sugar levels, but this is disrupted in people suffering from diabetes due to the DPP-IV enzyme.
"By inhibiting the overactive DPP-IV enzyme, the new substance can allow ...