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Rosiglitazone: failure of oversight or demons imagined?(EDITORIAL)

Journal of Family Practice

| September 01, 2007 | Susman, Jeff | COPYRIGHT 2003 Dowden Health Media, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Hey doc, I hear you're trying to kill me with that diabetes drug you got me on. So began my conversation with MJ, an overweight man with type 2 diabetes who, despite counseling, resolutely smokes a pack of cigarettes a day. Perhaps you've had a similar encounter with a patient of yours who's taking rosiglitazone (Avandia). As I write this, the news is awash with reports of the FDA Panel that voted 20-3 that rosiglitazone may increase the chances of a heart attack and 22-1 to keep the drug on the market. Small solace to the 7 million MJs worldwide who see some irony in remaining on a drug that has caused a "virtual public health emergency."

So where do we go from here?

Discussing the matter with patients is not easy, given that the facts are not…

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