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New analysis confirms heart risk linked to diabetes drugs.(Across Specialties)

Skin & Allergy News

| September 01, 2007 | Evans, Jeff | COPYRIGHT 2009 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Analysis of a wide array of studies and reports confirms an increased risk of heart failure in type 2 diabetes patients who take the thiazolidinedione drugs rosiglitazone and pioglitazone, even in patients who are young, take low doses, and lack heart failure history.

The findings should prompt a reevaluation of recommendations for the use of thiazolidinediones (TZDs) "even at low doses in NYHA [New York Heart Association] Stage I and II heart failure patients and in those with risk factors for heart failure," said Dr. Sonal Singh of Wake Forest University, Winston-Salem, N.C., and his colleagues (Diabetes Care 2007;30:2148-53).

The investigators conducted a…

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