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Growing brain cells: drugs that trigger the birth of neurons could provide the next generation of treatments for neurodegenerative diseases such as Parkinson's.(BIOTECHNOLOGY)(Brief article)

Technology Review

| September 01, 2006 | This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SOURCE: "Dopamine [D.sub.3] Receptor Agonist Delivery to a Model of Parkinson's Disease Restores the Nigrostriatal Pathway and Improves Locomotor Behavior" J. M. Van Kampen and C. B. Eckman

Journal of Neuroscience 26(27): 7272-7280

RESULTS: Scientists at the Mayo Clinic in Jacksonville, FL, found that a drug similar to ones used to treat Parkinson's disease can spur growth of new neurons in the substantia nigra, the brain area damaged in the disease. In a study of rodents genetically engineered to model Parkinson's disease, twice as much neurogenesis, or birth of new neurons, was seen in animals treated with the drug as in control animals. Many of the newly…

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