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Muromonab-CD3 (Systemic).
In the U.S. --
Orthoclone OKT3
In Canada --
Orthoclone OKT3
Monoclonal antibody
immunosuppressant
Description
Muromonab-CD3 (myoo-roe-MOE-nab cee-dee-three) is a monoclonal antibody. It is used to reduce the body's natural immunity in patients who receive organ (for example, kidney) transplants.
When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Muromonab-CD3 works by preventing the white blood cells from doing this.
The effect of muromonab-CD3 on the white blood cells may also reduce the body's ability to fight infections. Before you begin treatment, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
Muromonab-CD3 is to be administered only by or under the immediate supervision of your doctor. It is available in the following dosage form:
Parenteral
Injection (U.S. and Canada)
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For muromonab-CD3, the following should be considered:
- Muromonab-CD3 (Systemic).(Drug overview)
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language August 1, 2006 700+ words
...and benefits of the medicine with your doctor...comparing use of muromonab-CD3 in children...be caused by this medicine. Older adults -- Many medicines have not been studied...comparing use of muromonab-CD3 in the elderly...
- Muromonab-cd3 (Systemic).
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language January 1, 1997 700+ words
...and benefits of the medicine with your doctor...comparing use of muromonab-CD3 in children...be caused by this medicine. Older adults -- Many medicines have not been studied...comparing use of muromonab-CD3 in the elderly...
- MUROMONAB-CD3 (Intravenous route) - myoo-roe-MOE-nab-CD3.(Drug overview)
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language May 1, 2007 700+ words
...reaction to this medicine or any other medicines. Also tell your...comparing use of muromonab-CD3 in children...caused by this medicine. Older adults -- Many medicines have not been studied...comparing use of muromonab-CD3 in the elderly...
- Muromonab: nervous system complications.(Regulatory and Safety Action)
- Magazine article from: WHO Drug Information March 22, 2004 700+ words
Canada -- The manufacturer of muromonab-CD3 (Orthoclone OKT*3[R]) has...of important new safety information. Muromonab is used to treat acute rejection from...that do not respond to other therapies. Muromonab is not approved for use in children in...
- Cyclosporine (Systemic).
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language July 28, 2005 700+ words
...Children -- This medicine has been tested...adults. Other medicines -- Although...cyclosporine and these medicines increase the...Erythromycins (medicine for infection...cortisone-like medicine) or Cyclophosphamide...Purinethol) or Muromonab-CD3 (monoclonal...cyclosporine and these ...
- Cyclophosphamide (Systemic).
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language February 1, 2006 700+ words
...radiation or cancer medicines -- Cyclophosphamide...effects of these medicines or radiation therapy...toxicity of this medicine Cytarabine -- Cyclophosphamide...cortisone-like medicine) or Cyclosporine...Purinethol) or Muromonab-CD3 (monoclonal...blood. Since these medicines are used ...
- Cytarabine (Systemic).
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language February 1, 2006 700+ words
...radiation or cancer medicines -- Cytarabine may increase the effects of these medicines or radiation therapy...Corticosteroids (cortisone-like medicine) or Cyclosporine...Purinethol) or Muromonab-CD3 (monoclonal antibody...blood. Since these medicines are used to lower uric...
- Gemcitabine (Systemic).
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language February 1, 2006 700+ words
...Antithyroid agents (medicine for overactive thyroid...or other cancer medicines -- The risk of...cortisone-like medicine) or Cyclosporine...Purinethol) or Muromonab-CD3 (monoclonal...increase the effects of medicines by causing them...Proper Use of This Medicine Gemcitabine often...
- Topotecan (Systemic).
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language October 27, 2005 700+ words
...adults -- This medicine has been tested...younger adults. Other medicines -- Although certain...Antithyroid agents (medicine for overactive thyroid...or other cancer medicines -- The risk of...cortisone-like medicine) or Cyclosporine...Purinethol) or Muromonab-CD3 (monoclonal...
- Gemcitabine (Systemic).(Drug overview)
- USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language May 1, 2006 700+ words
...Antithyroid agents (medicine for overactive thyroid...or other cancer medicines -- The risk of...cortisone-like medicine) or Cyclosporine...Purinethol) or Muromonab-CD3 (monoclonal...increase the effects of medicines by causing them...Proper Use of This Medicine Gemcitabine often...