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Fortovase.
Pronounced: FORT-o-vace
Generic name: Saquinavir
Other brand name: Invirase
Why is this drug prescribed?
Fortovase is used in the treatment of advanced human immunodeficiency virus (HIV) infection. HIV causes the immune system to break down so that it can no longer fight off other infections. This leads to the fatal disease known as acquired immune deficiency syndrome (AIDS).
Fortovase belongs to a class of HIV drugs called protease inhibitors, which work by interfering with an important step in the virus's reproductive cycle. Fortovase is used in combination with other HIV drugs called nucleoside analogues (Retrovir or Hivid, for example). The combination produces an increase in the immune system's vital CD4 cells (white blood cells) and reduces the amount of virus in the bloodstream. Fortovase should not be used by itself.
The active ingredient in Invirase is saquinavir mesylate, and although it's similar to the active ingredient in Fortovase, the two drugs are not interchangeable (see "Most important fact about this drug"). However, the drug information provided here about Fortovase also applies to Invirase.
- Study Demonstrates New FORTOVASE(R) Dosing Strategy Maintains Low Viral Load...
- Press release article from: PR Newswire April 22, 2002 700+ words
...mesylate) with ritonavir (INVIRASE/r) or FORTOVASE/r, when given at the...Comparing pharmacokinetics of INVIRASE/r or FORTOVASE/r Two studies showed...saquinavir can be achieved with INVIRASE/r or FORTOVASE/r, dosed once- or twice...
- SAQUINAVIR (Fortovase or Invirase).
- Magazine article from: Research Initiative/Treatment Action! March 1, 2000 700+ words
...hard-gel, saquinavir mesylate or Invirase) for use in combination with nucleoside...formulation (saquinavir soft-gel or Fortovase) in November 1997. Guidelines classification...times a day. Saquinavir hard-gel (Invirase) is only recommended when combined...
- Fortovase.(Drug overview)
- PDR Family Guide to Prescription Drugs January 22, 2007 700+ words
...contain a similar ingredient, Fortovase and Invirase are not interchangeable...Norvir). Any switch from Invirase to Fortovase or vice versa should be made...you will not be able to use Fortovase. Invirase may be used only when it...
- Investigational Protease Inhibitor Fortovase(TM) (saquinavir) Compares...
- Press release article from: PR Newswire September 29, 1997 700+ words
...Data from a trial comparing FORTOVASE and INVIRASE in 171 HIV-infected, treatment...patients discontinued drug use (FORTOVASE and INVIRASE) due to clinical adverse...comparing the activity of INVIRASE to FORTOVASE with 171 patients. These...
- FDA Grants Roche Marketing Clearance for FORTOVASE(TM) (saquinavir)
- Press release article from: PR Newswire November 10, 1997 700+ words
...protease inhibitor, INVIRASE(R) (saquinavir mesylate). FORTOVASE is indicated for the...reflects the same cost as INVIRASE in the U.S. FORTOVASE will be available at...NV15355, which compared FORTOVASE and INVIRASE in 171 HIV-infected...
- Roche to Focus Resources on Availability of INVIRASE(R), Now Preferred...
- Press release article from: PR Newswire February 6, 2006 700+ words
...The efficacy of INVIRASE with ritonavir or Fortovase (with or without...standard of care. INVIRASE(R) (saquinavir...capsules and Fortovase(R) (saquinavir...antiviral regimen, Fortovase is the recommended formulation. INVIRASE is contraindicated...
- U.S. FDA Approves INVIRASE(R) Boosted With Ritonavir for Use in Treatment of...
- Press release article from: PR Newswire January 6, 2004 700+ words
...treatment. The efficacy of INVIRASE with ritonavir or Fortovase (with or without ritonavir...important to note that INVIRASE and Fortovase are not bioequivalent...considered standard of care. INVIRASE capsules and Fortovase soft gelatin capsules...
- Roche to Voluntarily Withdraw Anti-HIV Medication FORTOVASE(R) in Early 2006.
- Press release article from: PR Newswire May 18, 2005 700+ words
...The efficacy of INVIRASE with ritonavir or FORTOVASE (with or without...standard of care. INVIRASE(R) (saquinavir...capsules and FORTOVASE(R) (saquinavir...antiviral regimen, FORTOVASE is the recommended formulation. INVIRASE is contraindicated...
- Investigational Formulation of Invirase(R) Granted Priority Review Status by...
- Press release article from: PR Newswire August 17, 2004 700+ words
...The efficacy of Invirase with ritonavir or Fortovase (with or without...standard of care. Invirase capsules and Fortovase soft gelatin capsules...antiviral regimen, Fortovase is the recommended formulation. Invirase should not be administered...
- Study Shows No Significant Drug Level Interactions in Co-administration of...
- Press release article from: PR Newswire April 9, 2004 700+ words
...The efficacy of Invirase with ritonavir or Fortovase (with or without...standard of care. Invirase capsules and Fortovase soft gelatin capsules...antiviral regimen, Fortovase is the recommended formulation. Invirase should not be administered...