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Guanfacine (Systemic).
A commonly used brand name in the U.S. is Tenex.
Description Guanfacine (GWAHN-fa-seen) belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).
High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Guanfacine works by controlling ...
- Guanfacine extended release may benefit ADHD.(Behavioral Pediatrics)
- Magazine article from: Pediatric News Finn, Robert February 1, 2008 700+ words
...insomnia in two. Systolic blood pressure, diastolic blood pressure, and pulse rate tended to...with increasing doses of guanfacine, and then increased to baseline...greatest mean decrease in blood pressure was 10 mm Hg in week 4...
- Shire Announces Study Results With Once-Daily Guanfacine Extended Release (GXR)...
- Press release article from: PR Newswire November 16, 2006 700+ words
...In this clinical trial, guanfacine extended release significantly...individualized and optimal care." Guanfacine extended release was generally...systolic and diastolic blood pressure and pulse were reported. Guanfacine Extended Release Formulation...
- Extended-release guanfacine promising.(News)
- Magazine article from: Clinical Psychiatry News Finn, Robert February 1, 2008 700+ words
...extended release formulation of guanfacine (Intuniv, manufactured...randomly assigned to placebo or guanfacine extended release at a dose...diagnoses; and all had normal blood pressure and ECG results (Pediatrics...percentage of children in the guanfacine groups discontinued as a...
- FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended...
- Press release article from: PR Newswire Europe July 28, 2009 700+ words
...for abuse or dependence. Guanfacine, the active ingredient in...the mechanism of action of guanfacine in the treatment of ADHD...research supports the use of guanfacine for the treatment of ADHD...Small to modest changes in blood pressure, pulse rate, and ECG parameters...
- Lisdexamfetamine, guanfacine show benefit for ADHD: new studies affirm efficacy...
- Magazine article from: Pediatric News Kirn, Timothy F. August 1, 2007 700+ words
...given for a full year, and guanfacine, an investigational alpha2A...collaborating with Shire. Guanfacine, in an extended-release...modest changes were seen in blood pressure, pulse, and ECG in guanfacine patients. Dr. Sallee...
- Shire Announces Positive Results of Studies With Guanfacine Extended Release,...
- Press release article from: PR Newswire May 23, 2007 700+ words
...studies of the investigational medication guanfacine extended release (GXR, previously...in children aged 6 to 17 years. "Guanfacine extended release, the first selective...heart rate, and systolic and diastolic blood pressure were modest. In trial 304, common...
- SHIRE PLC - Shire Announces NDA Submission Guanfacine for ADHD.
- Press release article from: PR Newswire UK Disclose August 24, 2006 700+ words
SHIRE ANNOUNCES NDA SUBMISSION OF GUANFACINE EXTENDED-RELEASE FOR THE TREATMENT...FDA) for its investigational compound guanfacine extended release (previously referred...review period. "The NDA submission of guanfacine extended release is another Shire milestone...
- Shire Announces NDA Submission of Guanfacine Extended Release for the Treatment...
- Press release article from: PR Newswire August 24, 2006 700+ words
...FDA) for its investigational compound guanfacine extended release (previously referred...review period. "The NDA submission of guanfacine extended release is another Shire milestone...Shire plans to continue development of guanfacine extended release by initiating a Phase...