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Alpha 1-proteinase inhibitor, Human (Systemic).

USP DI-Volume II, Advice for the Patient: Drug Information in Lay Language

| January 01, 1997 | COPYRIGHT 1996 USP DIĀ® and Advice for the PatientĀ® are registered trademarks of USP used under license to Micromedex, Inc. (Hide copyright information)Copyright

A commonly used brand name in the U.S. and Canada is Prolastin.

Another commonly used name is alpha(sub 1)-antitrypsin.

Description Alpha(sub 1)-proteinase (AL-fa wun PRO-teen-ayce) inhibitor (alpha(sub 1)-PI) is used to treat emphysema caused by the lack of a certain protein, alpha(sub 1)-antitrypsin, in the body. This medicine replaces the protein when the body does not produce enough by itself.

Alpha(sub 1)-PI is prepared from human blood received from many donors. Each donor's blood is tested for human immunodeficiency virus (HIV) and hepatitis B virus before it is used to prepare this medicine. Also, alpha(sub 1)-PI is treated with heat to further reduce the risk of transmission of virus infections. However, no procedure has been found to be totally effective in removing viruses from blood products.

There have not been any reports of …

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