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Doppler shown superior to amnio in management of Rh disease.(Obstetrics)
RENO, NEV. -- Middle cerebral artery Doppler ultrasonography has better sensitivity and specificity for detecting severe maternal red cell alloimmunization than amniotic fluid bilirubin values, Dick Oepkes, M.D., said at the annual meeting of the Society for Maternal-Fetal Medicine.
He and his associates conducted a study of 164 pregnancies, in which severe anemia occurred in 74. They found that ultrasonography can safely replace determination of the deflection of the optical density of amniotic fluid at 450 nm, said Dr. Oepkes, director of the fetal medicine section of the department of obstetrics at the Leiden University Medical Center, the Netherlands.
"The Doppler is clearly the superior technique," he said. "The results of what we have found have confirmed what many people have directly implemented in their own centers already."
The study's 164 pregnancies were in women who had serum antibody titers indicative of Rh positivity with antigen-positive fetuses. The women underwent amniocentesis and ultrasonography at the same time and then had fetal ...
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Source: HighBeam Research, Doppler shown superior to amnio in management of Rh...