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More evidence points to need for second varicella shot.(Clinical Rounds)

Publication: Skin & Allergy News

Publication Date: 01-MAY-07

Author: Moon. Mary Ann
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COPYRIGHT 2007 International Medical News Group

The protection afforded by a single dose of the varicella vaccine steadily wanes over time, according to Dr. Sandra S. Chaves of the Centers for Dis ease Control and Prevention, Atlanta, and her associates.

A second vaccine dose could increase protection "by increasing the proportion of children with protective antibody titers and an improved cellular immune response," they added.

Several small chickenpox outbreaks have occurred in the United States, despite the success of the varicella vaccination program initiated in 1995. Investigations...

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