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Diabetes study shows unusual promise _ and risk.

Chicago Tribune (Chicago, IL)

| April 10, 2007 | COPYRIGHT 2007 Chicago Tribune. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Jeremy Manier

CHICAGO _ A new diabetes treatment developed at Northwestern University has allowed some patients to stop taking insulin for more than two years, but it also has spurred ethical objections from researchers who say the trial put Brazilian children at unnecessary risk.

Thirteen of the 15 patients in the a stem-cell study went off insulin for at least six months, prompting cautious excitement from some researchers who have seen the results, to be published Wednesday in the Journal of the American Medical Association. All of the patients had the less common form of diabetes called early-onset, or Type 1 diabetes, which normally requires close blood-glucose monitoring and long-term use of insulin injections.

The new approach, designed by Dr. Richard Burt of Northwestern, enlists a patient's own adult stem cells in an effort to halt the immune system's destruction of insulin-producing "beta" cells in the…

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