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Fragile X, Down Syndromes Linked to Faulty Brain Communication, Stanford Researcher Finds.

Business Wire

| April 10, 2007 | COPYRIGHT 2009 Business Wire. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

STANFORD, Calif. -- The two most prevalent forms of genetic mental retardation, Fragile X and Down syndromes, may share a common cause, according to researchers at Stanford University School of Medicine. The problem, a crippled communication network in the brain, may also be associated with autism.

Although the genetics of the disorders are very different, the end result for the brain seems to be the same, said Daniel Madison, PhD, associate professor of molecular and cellular physiology. "It's as if you had every light in your house wired to just one or two switches, rather than having many switches that can be flipped on or off in complex combinations to control the lighting in one room," he said.

Madison is the senior author of a paper on Fragile X syndrome in mice, which will be published in the April 11 issue…

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Source: HighBeam Research, Fragile X, Down Syndromes Linked to Faulty Brain Communication,...

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