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Test may help identify lung cancer at early stage.

Chicago Tribune (Chicago, IL)

| March 06, 2007 | COPYRIGHT 2007 Chicago Tribune. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Judy Peres

CHICAGO _ Scientists may be close to being able to predict who will develop lung cancer _ a development that could prevent tens of thousands of deaths a year in the U.S. alone.

Using a molecular test called a microarray, a research team from Boston University has come up with an 80-gene "signature" that can identify lung cancer at a very early stage in smokers. More importantly, the team showed that it is possible to detect pre-cancerous changes in normal tissue.

"It's like a molecular Pap smear," said Dr. Avrum Spira, who led the investigation.

The Pap test, which can detect abnormal cells in cervical tissue, is credited with greatly reducing deaths from cervical…

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