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Systemic inflammation: subclinical UTI may trigger acute coronary syndrome, study suggests.(News)
NEW ORLEANS -- Subclinical urinary tract infection may be an important proximate cause of acute coronary syndromes. Dr. John B. Sims said at the annual meeting of the American College of Cardiology.
His single-center, case-control, retrospective study showed that 27% of 100 consecutive patients had a urinary tract infection (UTI) at the time they presented to the hospital with an acute coronary syndrome (ACS), compared with only 11% of 100 matched control subjects undergoing elective coronary artery bypass graft surgery.
After adjustment for between-group differences in hyperlipidemia, history of hypertension, and other cardiovascular risk factors, the odds of having a UTI were 2.99-fold greater in patients with ACS than in controls, according to Dr. Sims of the University of Texas, Dallas.
A causative relationship between subclinical UTI and ACS is rendered plausible by the central role inflammation has ...
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Source: HighBeam Research, Systemic inflammation: subclinical UTI may trigger acute coronary...