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Case-control study: OC use before age 20 years tied to early breast cancer.(News)

OB GYN News

| May 15, 2004 | Zoler, Mitchel L. | COPYRIGHT 2004 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

ORLANDO, FLA. -- Oral contraceptive use by women before age 20 years was a significant risk factor for the development of breast cancer by age 40 in a case-control study in 245 Swedish women with early-onset breast cancer.

Although the risk of early oral contraceptive (OC) use is tentative based on this finding, the result raises enough concern to suggest that women younger than 20 years should avoid using an OC when alternative contraceptive options are available, Helena Jernstrom, Ph.D. said while presenting a poster at the annual meeting of the American Association for Cancer Research.

For example, an OC should probably not be used to treat acne in women younger than 20, said Dr. Jernstrom, professor of oncology at Lund (Sweden) University.

The study included 259 women diagnosed with a first, invasive breast cancer by the time they were 40 years old during 1990-1995 in the South Sweden Health Care Region; 245 of these women were included in the analysis, as well as three age-matched control subjects for each case.

Neither "ever" OC use nor current OC use was associated with breast cancer. But case subjects were 2.16-fold more likely to have used an OC before age ...

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