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Multifocal disease: smoking implicated in vulvar neoplasia.(Gynecology)
LAKE BUENA VISTA, FLA. -- Guilty or not guilty?
Dr. Theresa Freeman-Wang posed this question with regard to whether smoking is associated with the development of multifocal vulvar intraepithelial neoplasia, and rendered a "guilty" verdict as the result of a retrospective study.
Among 80 women with a histologically confirmed diagnosis of severe vulvar intraepithelial neoplasia (VIN III), 52 (65%) were current smokers, Dr. Freeman-Wang said at a meeting of the American Society for Colposcopy and Cervical Pathology.
"The invasive potential of VIN is high--at the very least 10 times higher than for cervical intraepithelial neoplasia, and we were trying to identify factors that might predict multifocal disease," she said.
The patients were seen between 1985 and 2002, and ranged in age from 19 to 94, with a mean age at presentation of 41.5 ...
- VIN III Needs Very Long-Term Follow-Up.
- Magazine article from: Family Practice News BAKER, BARBARA November 1, 1999 700+ words
...occurs on average more than 4 years after VIN III is diagnosed, according to a systematic review of almost 3,000 VIN III cases reported in the world literature...which occurred in 3.4% of cases after VIN III treatment, developed 4 months to 18...
- VIN III Follow-Up Should Span Several Years.(vulvar intraepithelial neoplasia)
- Magazine article from: OB GYN News BAKER, BARBARA November 1, 1999 700+ words
...occurs on average more than 4 years after VIN III is diagnosed, according to a systematic review of almost 3,000 VIN III cases reported in the world literature...which occurred in 3.4% of cases after VIN III treatment, developed 4 months to 18...
- Imiquimod Clears VIN III.(vulvar intraepithelial neoplasia III)
- Magazine article from: Family Practice News December 1, 1999 700+ words
...in Santa Fe, N.M. The patients had multifocal, human papilloma virus-associated vulvar intraepithelial neoplasia III (VIN III) that had been treated unsuccessfully with excision, laser surgery and other methods. Patients applied 5% imiquimod cream...
- BCC responds to hedgehog signal suppression.(Cutaneous Oncology)
- Magazine article from: Skin & Allergy News Bates, Betsy May 1, 2008 700+ words
...had locally advanced disease of the ear, and two had multifocal disease. Among four of the patients with metastatic disease...patients with clinically evaluable locally advanced or multifocal disease, two had a complete response and two had stable disease...
- T2 weighted MRI in assessment of volume changes during radiotherapy of high...
- Magazine article from: Journal of Cancer Research and Therapeutics Shukla, Divya Huilgol, Nagraj Trivedi, Naresh Mekala, C. October 1, 2005 700+ words
...patient and the differences were noted. Two patients with multifocal disease were excluded from the final analysis. Results: Of the...evaluable disease on pretreatment MRI's. Two patients with multifocal disease were not included in the final analysis. Five of our...
- Researchers' work from Memorial Sloan Kettering Cancer Center, Department of...
- Newspaper article from: Cancer Weekly October 13, 2009 700+ words
...lymph node involvement, nuclear grade, multicentric/multifocal disease, lymphovascular invasion (LVI), and extensive intraductal...lt;0.0001) and 1.6 times more likely to have multifocal disease (p <0.0001) compared with patients with luminal...
- New carcinoma study results from University of Toronto described.
- Newspaper article from: Cancer Weekly June 30, 2009 700+ words
...Bronchioloalveolar carcinoma (BAC) commonly presents as multifocal disease. Management of multifocal BAC remains controversial and...involved both lungs. The primary treatment modality for multifocal disease included surgical resection (78%), systemic therapy...
- Novel use of 308-nm excimer laser to treat a primary cutaneous CD30+...
- Magazine article from: Journal of Drugs in Dermatology Meisenheimer, John L. April 1, 2007 700+ words
...without extracutaneous involvement include radiotherapy and surgical excision. (1) Options for recurrent or multifocal disease include radiation therapy, systemic chemotherapy, and PUVA therapy. (1,3) [FIGURE 3 OMITTED] In this...
Source: HighBeam Research, Multifocal disease: smoking implicated in vulvar...