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Two new reports have found that some antidepressant drugs can increase the suicide risk for young adults and seniors. Such warnings already apply to children and teenagers, as previously reported.
The drug maker GlaxoSmithKline announced in a May 2006 letter to doctors that a meta-analysis of clinical trial data for its antidepressant paroxetine (Paxil) revealed an increase in suicidal behavior in two groups of adults compared with those who took placebo pills. The first group consisted of adults ages 18 to 24 who took Paxil for depression, anxiety, or obsessive-compulsive disorder. The second group, adults up to age 30, were being treated for depression.
Another study, in the May 2006 American Journal of Psychiatry, found a higher risk of suicide during the first month of therapy among patients age 66 and older who took selective serotonin reuptake inhibitors (SSRIs) compared with those who took other types of antidepressants. SSRIs studied included citalopram (Celexa), fluoxetine (Prozac), fluvoxamine (Luvox), Paxil, and sertraline (Zoloft).
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