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Gene therapy steadies erratic heartbeat in pigs; potential treatment for human arrhythmias.(Brief Article)

Transplant News

| December 15, 2000 | COPYRIGHT 1999 Transplant Communications, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

A gene therapy technique shown to steady irregular heartbeats in pigs may one day be useful in treating cardiac arrhythmias in humans.

Five pigs were treated with a modified adenovirus containing the gene that codes for the inhibitory G protein, a protein that is active in the heart's atrioventricular node and helps control heartbeat. After 1 week, measurements of electrical impulse rates confirmed that the gene was taken up into the pigs' heart…

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