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Preeclampsia tied to risk of early coronary disease: insulin resistance a shared factor.(News)
VIENNA -- Preeclampsia is a strong independent risk factor for development of premature coronary artery disease, Dr. Risto Juhani Kaaja said at the annual congress of the European Society of Cardiology.
In his case-control study, preeclampsia in any pregnancy independently conferred a 4.6-fold increased risk of documented coronary artery disease prior to age 65, placing it on a par as a coronary risk factor with current smoking, which was associated with a 4.2-fold increased risk.
Preeclampsia complicates 5%-10% of pregnancies. In light of these new findings linking it to increased coronary disease risk, it is particularly important to red-flag affected women and strongly encourage them to stop smoking, avoid obesity, and prevent or treat hyperlipidemia and hypercholesterolemia, said Dr. Kaaja of Helsinki (Finland) University. He reported on 141 parous women with coronary artery disease diagnosed prior to age 65 and 211 age-matched controls without known coronary disease. A history of preeclampsia was present in 21% of the coronary patients, compared with just 3% of controls.
Multiple logistic regression analysis identified several independent risk ...
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- Magazine article from: Family Practice News Jancin, Bruce December 15, 2003 700+ words
...controls without known coronary disease. History of preeclampsia...preeclampsia and coronary disease. Dr. Kaaja...factor in common: insulin resistance. He has demonstrated...preeclamptic pregnancy. Insulin resistance is gaining considerable...
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- Magazine article from: Heart Lawlor, D.A. Smith, G. Davey Mitchell, R. Ebrahim, S. April 1, 2004 700+ words
...heart disease and insulin resistance. Results: Coronary...with increased insulin resistance, increased triglyceride...explained by known coronary disease risk factors...heart disease, insulin resistance, dyslipidaemia...
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...These factors are key features of the insulin resistance syndrome, a group of metabolic disturbances...exploring the predictive power of insulin resistance have been conflicting, and while...cross sectional data suggest that insulin resistance could account for much of the enhanced...
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- Magazine article from: Heart Fisher, Miles March 1, 2004 700+ words
...are described in detail. * INSULIN RESISTANCE AND THE METABOLIC SYNDROME The concept of insulin resistance was first introduced in the 1960s...insulin to try and overcome the insulin resistance, and that this relative hyperinsulinaemia...
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- Magazine article from: Practice Nurse Mead, Mike July 5, 2002 700+ words
KEY POINTS * Insulin resistance is a decreased sensitivity...of healthy individuals with insulin resistance do not develop type 2 diabetes...in determining a patient's insulin resistance There are two underlying defects...
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- Magazine article from: Pediatric Nursing Scott, Leslie K. March 1, 2006 700+ words
The occurrence of insulin resistance and the components of insulin resistance syndrome (IRS) are rising in children (Steinberger & Daniels, 2003). Insulin resistance is a defective metabolic response to either...
- Insulin resistance.(Fortnightly Review)
- Magazine article from: British Medical Journal Krentz, Andrew J. November 30, 1996 700+ words
...that the clinical implications of insulin resistance reach far beyond that of the rare...remains about the association between insulin resistance and human disease.[2] For example...insulinaemia and other features of the insulin resistance syndrome can be identified in a proportion...
Source: HighBeam Research, Preeclampsia tied to risk of early coronary disease: insulin...