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Elevated NT, normal karyotype = good prognosis: 11-14 weeks' gestation.(Obstetrics)
PARIS -- Most karyotypically normal fetuses with elevated nuchal translucency at 11-14 weeks will be born without major abnormalities, Dr. Katia Bilardo reported at the 13th World Congress on Ultrasound in Obstetrics and Gynecology.
Sonographic assessment of nuchal translucency (NT) at 11-14 weeks' gestation is a recognized effective screening method for trisomy 21 and other chromosomal abnormalities. Up to 80% of aneuploid fetuses have increased NT, but so do 3%-5% of karyotypically normal fetuses, said Dr. Bilardo of the Academic Medical Centre, Amsterdam.
Over a 9-year period, 67% of 560 fetuses with elevated NT at 11-14 weeks had normal karyotypes. Of those 376, 81% were normal (detected by subsequent scans or after birth) while 19% had major adverse outcomes, including structural ...
- Studies from L.B. Daniels and co-authors have provided new information about...
- Newspaper article from: Biotech Week September 3, 2008 700+ words
...cardiovascular mortality); elevated NT-proBNP also predicted an...mortality). Those with both elevated NT-proBNP and detectable TnT...adults with detectable TnT or elevated NT-proBNP levels are at increased...article was prepared by Biotech Week editors from staff and other...
- Research reports from C.M. Korse and co-authors provide new insights into...
- Newspaper article from: Heart Disease Weekly October 25, 2009 700+ words
...was found in 15 (15%) of 102 patients, 13 of whom had elevated NT-proBNP levels. In the univariate proportional odds model...The researchers concluded: "Furthermore, patients with elevated NT-proBNP in addition to elevated CgA levels showed worse overall...
- Research Suggests That Cardiac Marker NT-proBNP is a Better Predictor for...
- Press release article from: Business Wire December 1, 2005 700+ words
...R.J. van Kimmenade, et al. The study concluded that elevated NT-proBNP concentration in the presence of a low GFR strongly...predictor of mortality irrespective of kidney disease (KD). Elevated NT-proBNP levels in KD patients frequently indicate underlying...
- Research from Libin Cardiovascular Institute in the area of heart attack risk...
- Newspaper article from: Heart Disease Weekly March 29, 2009 700+ words
...measured 2-4, 6-10, and 14-18 weeks after MI. The median age of the 100...accuracy (26%) than a single, markedly elevated NT-BNP measurement. A moderately and persistently elevated NT-BNP in the early post-MI period was...
- Research from S. Picciotto and co-authors yields new data on heart attack risk...
- Newspaper article from: Heart Disease Weekly February 15, 2009 700+ words
...traditional cardiovascular risk factors," wrote S. Picciotto and colleagues, . The researchers concluded: "Patients with elevated NT-proBNP, respiratory symptoms or obesity had higher IL-6 concentrations and may potentially be at greater risk for coronary...
- Marker signals CAD in renal disease.(CLINICAL CAPSULES)(coronary artery...
- Magazine article from: Internal Medicine News Moon, Mary Ann October 1, 2005 700+ words
...to Christopher R. deFilippi, M.D., and his associates at the University of Maryland, Baltimore. The significance of elevated NT-proBNP levels in this patient population has been uncertain because clearance of the peptide was thought to depend on renal...
- Human Heparanase: A Molecular Determinant of Tumor Metastasis and Angiogenesis.
- Newspaper article from: Cancer Research Alert December 1, 2000 700+ words
...heparanase can play important roles in melanoma progression, with the brain considered the ideal target organ because of the elevated NT production and the strong angiogenic properties of melanoma cells found in the brain. Of equal importance, we have po
- New kidneys study results reported from L.H. Bernstein et al.(Report)
- Newspaper article from: Heart Disease Weekly August 30, 2009 700+ words
...interpreting NT-proBNP levels based on GFR, independent of age. This study includes 247 pts in whom CHF and known confounders of elevated NT-proBNP were excluded, to show the relationship of GFR in association with age. The effect of cGFR on NT-proBNP level...