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Phenylephrine gel treats fecal incontinence without surgery. (Investigational Agent).

OB GYN News

| February 15, 2003 | Jancin, Bruce | COPYRIGHT 2003 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

ST. LOUIS -- Phenylephrine gel is a promising nonsurgical therapy for fecal incontinence, Dr. Wayne B. Tuckson said at 'the 12th International Pelvic Reconstructive and Vaginal Surgery Conference.

When applied around the anus, this topical therapy boosts defectively low resting anal pressures to within normal range. But it's not for everyone with fecal incontinence, as it requires intact internal anal sphincter muscles, said Dr. Tuckson, a colorectal surgeon at the University of Louisville (Ky.), who has no financial interest in the product.

"It's very useful for the patient with internal anal sphincter deficiency where the muscle has been stretched and doesn't regain its normal tone," he explained.

Phenylephrine gel (Incostop) is an investigational agent in phase III development. Earlier this ...

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