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Large study shows early-stage ovarian cancer still eludes ultrasound screening: low detection rate in high-risk women. (News).
NEW YORK -- A total of 11,500 gynecologic ultrasound screenings in 4,150 asymptomatic women at high risk for ovarian cancer did not find a single stage I ovarian cancer, Dr. Leeber Cohen said at the 12th World Congress on Ultrasound in Obstetrics and Gynecology.
Data combined from Yale University New Haven, and Northwestern University Chicago, from a 5- to 10-year period (depending on the program) showed that pelvic ultrasound screening in asymptomatic high-risk women detected six malignancies--two fallopian tube cancers, two stage III ovarian cancers, and two stage III peritoneal cancers-but no early ovarian cancers. All the women with cancer had normal ultrasound screens 6-12 months before detection.
"The role for ultrasound screening of stage I ovarian cancer, particularly in high-risk women, is not established," said Dr. Cohen of Northwestern University Chicago.
Previous studies have shown that ultrasound is effective in identifying advanced-stage ovarian cancer. Color Doppler can improve the specificity of ultrasound screening for advanced disease. Three-dimensional ultrasound as yet is a research tool for ovarian cancer screening, he added.
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