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More data support breast-conserving surgery. (Phase I or II Cancer).
CHICAGO -- Follow-up to a National Cancer Institute trial indicates a modified radical mastectomy is no better for women with phase I or II cancer than breast-conserving surgery
These results echo the recently released findings of a 20-year follow-up of women who took part in two clinical trials comparing mastectomy with breast-conserving surgery in the 1970s and 1980s. Both trials failed to observe a survival advantage to mastectomy after 20 years among 1,851 patients in the United States and 701 patients in Italy Dr. Matthew Poggi at the annual meeting of the Radiological Society of North America.
Dr. Poggi said the biggest distinction between the current NCI trial and the other trials is the NCI trial did not require negative rumor margins. He could not say how many women had positive margins as some surgeries were performed at other institutions, but he estimated it at roughly 20%.
The NCI trial was conducted between 1979 and 1987. A total of 116 women were randomized to modified radical mastectomy and 121 to lumpectomy plus radiation. Radiation therapy was 4,500-5,040 cGy in 180 cGy administered five times a week for 5-5.5 weeks. All were given one boost, but no chest wall radiation was given, Dr. ...
- Radiotherapy improves survival after early stage, breast-conserving surgery.
- Newspaper article from: Biotech Business Week February 9, 2004 700+ words
...omission of radiotherapy after breast-conserving surgery for early-stage breast cancer is...stage breast cancer who have breast-conserving surgery followed by radiotherapy have similar...breast cancer who underwent breast-conserving surgery alone or surgery followed by radiotherapy...
- Breast-conserving surgery and radiation therapy underutilized. (Fred Hutchinson...
- Newspaper article from: Cancer Weekly January 20, 1992 700+ words
...Hutchinson Cancer Research Center Breast-conserving surgery is not performed on the majority...study found that use of breast-conserving surgery has actually declined since 1985...procedure. The likelihood of breast-conserving surgery was found to decrease with increasing...
- Study: Breast-conserving surgery viable option for cancer involving...
- Newspaper article from: Cancer Weekly April 6, 2004 700+ words
...net) -- For many years, breast-conserving surgery has been the standard of care for...large randomized studies of breast-conserving surgery done in the 1980s and 1990s. A study...can successfully undergo breast-conserving surgery. Members of the department of surgery...
- New Study from Abington Memorial Hospital Indicates Breast Conserving Surgery...
- Press release article from: PR Newswire March 12, 2004 700+ words
...PRNewswire/ -- For many years, breast conserving surgery has been the standard of care for...large randomized studies of breast conserving surgery done in the 1980s and 1990s. A study...areola can successfully undergo breast conserving surgery. Members of the Department of Surgery...
- Radiation and tamoxifen after breast-conserving surgery reduce tumor recurrence.
- Newspaper article from: Medical Devices & Surgical Technology Week July 25, 2004 700+ words
...Radiation and tamoxifen after breast-conserving surgery reduce tumor recurrence. "To study...radiotherapy and tamoxifen after breast-conserving surgery (BCS) in patients with a favorable...Radiation therapy after breast-conserving surgery: first results of a randomised clinical...
- Locoregional recurrence is lower in recent years after breast-conserving...
- Newspaper article from: Medical Devices & Surgical Technology Week May 9, 2004 700+ words
...rates of recurrence after breast-conserving surgery, researchers say. "The aim of...recurrence (LRR) rates after breast conserving surgery and mastectomy between the time periods...which 385 were removed by breast conserving surgery and 879 by mastectomy. During follow...
- Breast-conserving Surgery Plus Radiation Good for Older Women, Too.
- Press release article from: PR Newswire August 31, 2004 700+ words
...any age. This study sought to evaluate whether breast-conserving surgery plus radiation was as effective for older women as it...to avoid a disfiguring mastectomy and opt for breast-conserving surgery plus radiation," said Bruno Cutuli, M.D. lead author...
- Paper on Breast Conserving Surgery.
- News wire article from: Asia Africa Intelligence Wire October 28, 2005 700+ words
...Center will be presenting a paper on the topic of "Breast Conserving Surgery- A New Concept in Pakistan" in International Network...years with early stage breast cancer who had breast-conserving surgery. This will also convince more and more surgeons to accept...
- ASTRO Provides Treatment Information on Breast Cancer; Options Include...
- News wire article from: The America's Intelligence Wire October 6, 2005 700+ words
...treatments for the disease to include a combination of breast-conserving surgery and radiation therapy. In the past, the only treatment...stage breast cancer include the less-radical breast-conserving surgery (lumpectomy) followed by radiation therapy and sometimes...
- Risk of second non breast malignancies (SNBM) in relation to Brca1 and Brca2...
- Magazine article from: American Journal of Immunology Kirova, Youlia M. Fourquet, Alain Savignoni, Alexia Sigal-Zafrani, Brigitte Stoppa-Lyonnet, Dominique July 1, 2006 700+ words
...cohort of women with small cancers treated with breast conserving surgery and radiotherapy at our Institut from 1981 to 2000. The...of women with small breast cancers treated with breast conserving surgery and radiotherapy at the Institut Curie from 1981 to 2000...
Source: HighBeam Research, More data support breast-conserving surgery. (Phase I or II Cancer).