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CHICAGO -- Treatment with metformin appeared to cut the risk of gestational diabetes in a study of 72 women with polycystic ovary syndrome.
The women together had a total of 76 pregnancies during which they were treated with metformin; the incidence of gestational diabetes in these pregnancies was 8%, Dr. Charles J. Glueck reported in a poster at the annual scientific sessions of the American Heart Association.
In contrast, 39 other women with polycystic ovary syndrome (PCOS) who were not diabetic and were not treated with metformin but were managed at the same medical center had a 23% incidence of gestational diabetes.
Prior reports have established that gestational diabetes occurs in 25%-45% of women with PCOS. In contrast, the risk of gestational diabetes among the general population in the United States is 1%-4%, explained Dr. Glueck, medical director of the Cholesterol ...
Source: HighBeam Research, Metformin may block gestational diabetes. (Polycystic Ovary Syndrome).