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BRCA1 mutations tied to raised risk of other cancers. (Beyond Breast Cancer).
Women carrying BRCA1 mutations had approximately twice the overall risk of developing cancer at sites other than the breast or ovary in a cohort study of almost 12,000 people.
Compared with the general population, women with RRCA1 mutations were at increased risk of developing cancer of the liver (relative risk 4.06), cervix (relative risk 3.72), uterine body (relative risk 2.65), pancreas (relative risk 2.26), and colon (relative risk 2.03). In general, estimated relative risks for mutation carriers were greater for those under age 65, reported Dr. Deborah Thompson of the University of Cambridge (England) and her colleagues.
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Source: HighBeam Research, BRCA1 mutations tied to raised risk of other cancers. (Beyond Breast...