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SAN ANTONIO -- A series of four simple, clinical factors can identify postmenopausal women with osteopenia who face the highest risk of a bone fracture.
The most powerful of these predictors is a prior history of fracture, Dr. Paul D. Miller reported in a poster at the annual meeting of the American Society for Bone and Mineral Research.
Postmenopausal women with osteopenia and a prior history of-fracture had a 4.1% incidence of osteoporotic fractures over the following year, a rate that was nearly as high as the 4.3% annual fracture incidence among women with outright osteoporosis.
In addition to a prior history of fracture, the other three factors that identify increased fracture risk were a bone mineral density score of -1.8 or less, fair or poor health status, and poor mobility.
All together, the four factors flagged 74% of the women with osteopenia who went on to have a fracture during their first year of follow-up, said Dr. Miller, medical director of the Colorado Center for Bone Research in Lakewood.
The fracture risk faced by women with osteopenia--defined as a T-score between -1 and -2.5-was assessed by analyzing data collected from 57,421 postmenopausal white women with osteopenia who ...