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Clinical factors flag women with high fracture risk. (Osteopenic, Postmenopausal Women).

OB GYN News

| January 01, 2003 | Zoler, Mitchel L. | COPYRIGHT 2003 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SAN ANTONIO -- A series of four simple, clinical factors can identify postmenopausal women with osteopenia who face the highest risk of a bone fracture.

The most powerful of these predictors is a prior history of fracture, Dr. Paul D. Miller reported in a poster at the annual meeting of the American Society for Bone and Mineral Research.

Postmenopausal women with osteopenia and a prior history of-fracture had a 4.1% incidence of osteoporotic fractures over the following year, a rate that was nearly as high as the 4.3% annual fracture incidence among women with outright osteoporosis.

In addition to a prior history of fracture, the other three factors that identify increased fracture risk were a bone mineral density score of -1.8 or less, fair or poor health status, and poor mobility.

All together, the four factors flagged 74% of the women with osteopenia who went on to have a fracture during their first year of follow-up, said Dr. Miller, medical director of the Colorado Center for Bone Research in Lakewood.

The fracture risk faced by women with osteopenia--defined as a T-score between -1 and -2.5-was assessed by analyzing data collected from 57,421 postmenopausal white women with osteopenia who ...

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