AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Statin no better than usual care in reducing risk of morbidity, mortality.
2003 JAN 8 - (NewsRx.com & NewsRx.net) -- Pravastatin, a statin drug used to reduce cholesterol, does not reduce the death rate or incidence of coronary heart disease events in patients with moderately high cholesterol and well-controlled high blood pressure, when compared to usual care, according to researchers in Texas and Washington.
The role levels of low-density lipoprotein cholesterol (LDL-C, the "bad" cholesterol) play in the development of coronary heart disease (CHD) is well-established. Trials in the 1970s and 1980s showed that lowering LDL-C reduced the incidence of CHD-related events such as heart attack, but the average reduction in LDL-C for these trials was only 10%.
In the 1980s, a more powerful class of drugs, statins, were developed which could reduce total cholesterol by approximately 20% or more. Studies have demonstrated that statins administered to individuals with risk factors for CHD reduce CHD events. However, many of these…
- ALLHAT: new questions. (Guest Editorial).(Antihypertensive and Lipid-Lowering...
- Magazine article from: Family Practice News Abrams, Jonathan April 15, 2003 700+ words
...The lipid arm of ALLHAT, conducted in a subset...pravastarin subjects and usual-care subjects by the end of...statin drop-ins in the usual-care group and because of...pravasratin. The findings of ALLHAT establish the therapeutic...
- Data challenged; ALLHAT study is flawed, PI says.
- Newspaper article from: Genomics & Genetics Weekly January 31, 2003 700+ words
...GenoMed, Inc., announced that the ALLHAT study published in a recent issue of Journal...Association has a fatal research flaw. ALLHAT, an 8-year study funded by the National...only 50% of the enzyme activity. The ALLHAT investigators should have used one of...
- GenoMed Announces ALLHAT Study is Fatally Flawed.
- Press release article from: PR Newswire December 18, 2002 700+ words
...genomics company, announced today that the ALLHAT study published in today's Journal of...Association has a fatal research flaw. ALLHAT, an 8 year study funded by the National...only 50% of the enzyme activity. The ALLHAT investigators should have used one of...
- Drug treatment of hypertension: implications of ALLHAT.(antihypertensive and...
- Magazine article from: Heart Williams, B. June 1, 2003 700+ words
...of antihypertensive treatment, the ALLHAT trial, has led to some controversial...treatment to prevent heart attack trial (ALLHAT) has generated much interest and opinion. (1) This is because (1) ALLHAT is the largest ever study of antihypertensive...
- ALLHAT continues to stir clinical controversy.(Cardiovascular...
- Magazine article from: Internal Medicine News Peck, Peggy August 1, 2004 700+ words
NEW YORK -- ALLHAT, the trial that was supposed to end the...Society of Hypertension. For example, ALLHAT (Antihypertensive and Lipid-Lowering...the new-onset diabetes findings. "ALLHAT says these metabolic abnormalities did...
- ALLHAT data to drive JNC-VII recommendations. (Results Expected in...
- Magazine article from: Internal Medicine News Mulcahy, Nicholas August 15, 2002 700+ words
NEW YORK -- We're all waiting for ALLHAT. Chalk up last year's decision to delay...Treatment to Prevent Heart Attack Trial (ALLHAT) are expected in December. The JNC updates...and Blood Institute--the sponsor of ALLHAT as well as the convener of the committees...
- Think thiazides are old hat? ALLHAT says think again: outcomes support...
- Magazine article from: Journal of Family Practice Mendoza, Michael D. Stevermer, James J. May 1, 2008 700+ words
...Treatment to Prevent Heart Attack Trial (ALLHAT). Arch Intern Med. 2008; 168:207...Treatment to Prevent Heart Attack Trial (ALLHAT). (1) This new subgroup analysis supports...the past. Studies published before this ALLHAT subgroup analysis showed that hydrochlorothiazide...
- ALLHAT: new questions. (Guest Editorial).(Editorial)
- Magazine article from: Internal Medicine News Abrams, Jonathan April 15, 2003 700+ words
...Initiative, the unexpected findings of ALLHAT challenged our too-frequent reliance...recent randomized, controlled trials. ALLHAT, coordinated by the National Heart...beta]-blockers were not tested in ALLHAT, but these drugs were a part of second...
- Hypertension study fails to end clinical debate; ALLHAT found increase in...
- Magazine article from: Clinical Psychiatry News October 1, 2004 700+ words
NEW YORK -- ALLHAT, the trial that was supposed to end the...Society of Hypertension. For example, ALLHAT (Antihypertensive and Lipid-Lowering...the new-onset diabetes findings. "ALLHAT says these metabolic abnormalities did...
- Diuretics deemed best first-line tx for hypertension: study shows thiazides...
- Magazine article from: Internal Medicine News Peck, Peggy January 1, 2003 700+ words
...finding from the long-awaited results of ALLHAT--the Antihypertensive and Lipid-Lowering...failure," Dr. Wright, vice chair of the ALLHAT steering committee and lead author on...blood pressure in check. Looking at the ALLHAT results, it is dear that by the end of...
Source: HighBeam Research, Statin no better than usual care in reducing risk of morbidity,...
Other Gale sites: Encyclopedia.com | HighBeam Research | Acquire Content | Books & Authors | Goliath | MovieRetriever | Smart QandA
The AccessMyLibrary advertising network includes:
