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Statin no better than usual care in reducing risk of morbidity, mortality.

Biotech Week

| January 08, 2003 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JAN 8 - (NewsRx.com & NewsRx.net) -- Pravastatin, a statin drug used to reduce cholesterol, does not reduce the death rate or incidence of coronary heart disease events in patients with moderately high cholesterol and well-controlled high blood pressure, when compared to usual care, according to researchers in Texas and Washington.

The role levels of low-density lipoprotein cholesterol (LDL-C, the "bad" cholesterol) play in the development of coronary heart disease (CHD) is well-established. Trials in the 1970s and 1980s showed that lowering LDL-C reduced the incidence of CHD-related events such as heart attack, but the average reduction in LDL-C for these trials was only 10%.

In the 1980s, a more powerful class of drugs, statins, were developed which could reduce total cholesterol by approximately 20% or more. Studies have demonstrated that statins administered to individuals with risk factors for CHD reduce CHD events. However, many of these…

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Source: HighBeam Research, Statin no better than usual care in reducing risk of morbidity,...

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