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Comparison of human, mouse genomes show genomic rearrangements to account for evolution.
2003 JAN 1 - (NewsRx.com & NewsRx.net) -- A leading expert in computational biology at the University of California, San Diego (UCSD) estimates that it took many more evolutionary genome rearrangements than previously thought - both large and small - to account for differences in the human and mouse genomes.
The findings of Jacobs School of Engineering computer science and engineering professor Pavel Pevzner and project scientist Glenn Tesler are included in two landmark papers.
In the December 5, 2002, issue of the journal Nature, Pevzner and other scientists in the 31-institution Mouse Genome Sequencing Consortium published a near-final genetic blueprint of a mouse, together with the first comparative analysis of the mouse and human genomes. In a companion paper published in the December 4, 2002, Genome Research journal, Pevzner and Tesler (in collaboration with Michael Kamal and Eric Lander at the Whitehead/MIT Center for Genome Research) analyze human-mouse genome rearrangements for insights about the evolution of mammals, and outline their…
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...analyze human-mouse genome rearrangements for insights about...micro-level genome rearrangements. They conclude...very similar, genome rearrangements have occurred...The human and mouse genome sequences can...
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- Press release article from: Business Wire April 27, 2001 700+ words
...has completed the assembly of the mouse genome. Celera, which began sequencing...approximately 6X-fold coverage of the mouse genome, ensuring greater than 99 percent representation of the mouse genome. The next phase of Celera's research...
- Mouse genome: clue to humans.
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...this week's announcement that the mouse genome has been mapped. Celera Genomics...week it had completed 99 percent of the mouse genome map. The Rockville, Md.-based company...Biosystems in Foster City, to map the mouse genome. The two companies are collaborating...
- Celera Finishes Mouse Genome.(Brief Article)
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...removed from offering an annotated mouse genome with sixfold coverage. The Rockville...the only source with an assembled mouse genome, available immediately. "The significance of the mouse genome itself is important, but what's...
- International team of researchers assembles draft sequence of mouse genome.
- Newspaper article from: Genomics & Genetics Weekly June 7, 2002 700+ words
...advance in genomics, the international Mouse Genome Sequencing Consortium has announced...databases an advanced draft sequence of the mouse genome - the genetic blueprint for the most...draft sequence was assembled by the Mouse Genome Sequencing Consortium, an international...
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- Newspaper article from: Genomics & Genetics Weekly September 6, 2002 700+ words
...the genetics makeup of a mouse - the mouse genome - is 98% complete and is being released...map gives us the big picture of the mouse genome. It will be tremendously helpful to...using current methods. The physical mouse-genome map is a complementary effort to the...
- Building a better mouse genome: transcriptome information and a comparison of...
- Magazine article from: The Scientist Anderson, Maria W. July 19, 2004 700+ words
...its genome. In December 2002, the Mouse Genome Sequence Consortium (MGSC), led by...Louis, published an analysis of the mouse genome. (1) The MGSC generated a draft sequence...sequence. They found the 2.5-Gb mouse genome to be 14% smaller than the human genome...
- Physical Map of Mouse Genome Now Available.
- News wire article from: Ascribe Higher Education News Service August 4, 2002 700+ words
...the genetic makeup of a mouse -- the mouse genome -- is 98 percent complete and is being...map gives us the big picture of the mouse genome. It will be tremendously helpful to...using current methods. The physical mouse-genome map is a complementary effort to the...
- International Consortium Decodes Mouse Genome; Institute for Systems Biology...
- Press release article from: Business Wire December 5, 2002 700+ words
...completed the initial analysis of the mouse genome. This achievement will help scientists...Getting this kind of insight into the mouse genome can give us a better understanding of...experimental model for human diseases, the mouse genome has always been first in line among...
- Scientists succeed in decoding mouse genome.
- News wire article from: Chicago Tribune (Chicago, IL) December 4, 2002 700+ words
...unreadable. Many scientists believe the mouse genome will provide them with a sort of Rosetta...researchers said the nearly completed mouse genome provides the key to deciphering the...billion chemical letters of life, the mouse genome is a remarkable duplicate version of...
Source: HighBeam Research, Comparison of human, mouse genomes show genomic rearrangements to...
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