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Rosiglitazone-associated hepatic and cardiovascular events.
Canada -- Between March 2000 and February 2001, 166 rosiglitazone (Avandia[R])-associated adverse drug reactions were reported to the Canadian Adverse Drug Reaction Monitoring Program (CADRMP). Of these, 38 were classified as serious; with 20 reports of cardiovascular disorders, 10 of liver and biliary disorders, and 8 of haematological disorders.
To minimize the risk of hepatic and cardiovascular reactions with rosiglitazone, …
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