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Supply of vaccines world-wide has changed significantly over the past several years. As an example, several countries formerly relying on centralized procurement through UNICEF and WHO are now responsible for purchasing their own vaccines. Additionally, donor agencies previously using the WHO/UNICEF system are increasingly working with commercial agents to purchase vaccines. These changes, which imply a commitment by countries to support their own immunization programmes, are reassuring. However, the jump from dependence on the WHO/UNICEF system to independence is not easy and many countries have benefited from WHO's expertise and experience.
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