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Slow-release garlic may counter atherosclerosis. (Placebo-Controlled Trial).

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| December 01, 2002 | Evans, Jeff | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

BETHESDA, MD. -- A sustained-release garlic preparation led to decreased intima-media thickness of the common carotid arteries in a 24-month study of 103 men with atherosclerosis, Dr. Igor Sobenin reported at a meeting on the cardiovascular effects of botanicals sponsored by the National Institutes of Health.

In the double-blind, multicenter study, 103 similar men received placebo tablets. All subjects were 40-74 years old. They were randomly assigned to twice-daily use of a placebo tablet or an Allicor tablet (INAT-Farma Ltd., Moscow). Each Allicor tablet contains 150 mg of garlic powder and a polymeric matrix that allows the slow release and intestinal absorption of biologically active components.

Ultrasound monitoring revealed significant decreases in intima-media thickness at 12, 18, and 24 months in patients who received Allicor. At 24 months, the average decrease was 44 [micro]m with Allicor and 29 [micro]m with placebo. The thickness decreased in 81% of Allicor patients and in 21% of ...

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