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SAN DIEGO -- The chance that a patient with a normal TSH level will be found to have an abnormal free thyroxine level is 1%, according to a study that steps into the controversy over whether only one or both tests are needed to adequately evaluate a patient's thyroid function.
"The TSH alone is adequate to screen out patients with thyroid dysfunction, and limiting free T4 tests to just those with abnormal TSHs would result in considerable cost savings," the study's presenter, Dr. Anthony J. Viera, said at the annual meeting of the American Academy of Family Physicians.
In Dr, Viera's study, he reviewed the records of all thyroid function tests from his family medicine clinic at Naval Hospital Jacksonville (Fla.) from January 1995 to March 1997. There were 2,932 TSH tests and 2,861 T4 tests ordered during that time. Most of the time, the tests were ordered together (98%), and the T4 was never ordered alone.
When he excluded the single TSH tests and the duplicate tests, he was left with a sample of 1,392 paired tests for evaluation. Ninety-six percent of those tests were concordant, meaning that the patient was euthyroid, with normal values for both tests (1,187), hypothyroid, with an elevated TSH level and a depressed T4 level (112), or hyperthyroid, with a low TSH level and an elevated T4 level ...
Source: HighBeam Research, Two thyroid measures unnecessary, study says. (TSH Alone is Adequate).