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RANCHO MIRAGE, CALIF. -- More than a quarter of all pregnancies were complicated by at least one major medical condition in a large, cross-sectional cohort study representing the vast majority of births during 1 year in California.
Topping the list of complications were preterm gestation, hypertension, diabetes mellitus, and malpresentation, reported Dr. Kimberly D. Gregory at the annual meeting of the Pacific Coast Obstetrical and Gynecological Society. Consistently, mothers who were at least 35 were more likely to have complicated pregnancies and births than were younger mothers when hospital discharge data from 1995 were combed for the presence of 31 clinical conditions.
Race and ethnicity of mothers had a variable effect on pregnancy-related complications, but African American women, and older African American mothers especially, faced considerably higher risk than mothers from other ethnic groups. While 26% of 443,532 births were complicated by at least one medical condition, 33% of African Americans had at least one pregnancy-related complication, said Dr. Gregory, director of women's health services research at Cedars-Sinai Medical Center in Los Angeles.
Other ethnic groups were at higher risk for a few medical conditions; for example, non-Hispanic white women were most likely to have pregnancies complicated by cardiac disease and isoimmunization, and Hispanic women had elevated rates of diabetes mellitus, severe hypertension, and multiple gestation.
Women from other ethnic groups had elevated risks of diabetes mellitus and hepatitis.
But African American women were at significantly increased risk for 10 major conditions. (See chart.) Younger African American mothers were at increased risk for four more.
Further research is needed to identify the biologic and/or social mechanisms that might explain why African American women ...
Source: HighBeam Research, Complications Mar one-quarter of pregnancies. (Large California...