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CELEBREX AND VIOXX: ARE THEY SAFER THAN THE OLDER ANTI- INFLAMMATORY DRUGS?(Brief Article)

HealthFacts

| September 01, 2001 | Napoli, Maryann | COPYRIGHT 1999 Center for Medical Consumers, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Ever since the anti-inflammatory drugs, Celebrex and Vioxx, came on the market two and a half years ago, questions have surrounded them. Do these costly drugs offer a safer alternative to other arthritis drugs? Do they have a lower rate of the gastrointestinal side effects associated with older painkillers, such as aspirin, ibuprofen, and acetaminophen? If so, is this benefit canceled by heart-related risks linked to Celebrex and Vioxx?

A new analysis of all clinical trials that had attempted to answer these questions was conducted by Debabrata Mukherjee, MD, and colleagues at the Cleveland Clinic Foundation. But before their analysis appeared in the Journal of the American Medical…

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Makers of Pain Pills Celebrex, Vioxx Seek Cure for Their Doldrums.: News wire article from: Record (Hackensack, NJ) October 28, 2001 700+ words
...traditional painkillers. But Celebrex and Vioxx are losing their superstar aura...comparable stomach benefits of Celebrex and Vioxx over older medicines. The new...products' continued growth. Celebrex and Vioxx are wildly popular among physicians...


Study shows Celebrex appears to be safer than Vioxx.: Newspaper article from: World Disease Weekly December 28, 2004 700+ words
...inhibitors may carry similar dangers. "Vioxx and Celebrex look different. Relative to Celebrex, Vioxx had about a threefold greater risk of...problems. Studies done 5 years ago, when Celebrex and Vioxx were approved, suggest the same mechanism...


Head to head struggle ;Initial Celebrex, Vioxx ad spending, sales...: Magazine article from: Advertising Age Rosenberg, Janice April 3, 2000 700+ words
...371 million for Vioxx. In the first month Celebrex was available in the...family. MOVING FAST Vioxx, released May 1999...Co., is giving Celebrex a run for its money...lives. Together, Vioxx and Celebrex captured a 21% share...


Vioxx scare puts heat on Celebrex.: Newspaper article from: Knight Ridder/Tribune Business News October 7, 2004 700+ words
...revealing a mechanism" in both Vioxx and Celebrex that could "predispose people...Vioxx for at least 18 months. Vioxx, Celebrex and Bextra are the only three...billion for Merck last year. Celebrex and Vioxx have become household names...


JAMA article suggests Celebrex, Vioxx carry cardiac risk.(Journal of the...: Magazine article from: Drug Store News WEST, DIANE September 24, 2001 700+ words
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In Large Head-to-Head COX-2 Inhibitor Safety Study, Vioxx(R) Associated with...: Press release article from: PR Newswire June 22, 2000 700+ words
...provides compelling evidence that Celebrex and Vioxx affect hypertensive arthritis...60 percent more patients on Vioxx than on Celebrex (a 1.6-fold higher incidence...blood pressure levels between Celebrex and Vioxx was observed as early as week...


Study: Vioxx ups pressure; Celebrex doesn't.: News wire article from: Knight Ridder/Tribune Business News January 27, 2005 700+ words
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CHIMIE HEBDO: Journal of American Medical Association study calls safety of...: News wire article from: Chemical Business Newsbase September 14, 2001 700+ words
...inhibitors (such as Merck's Celebrex and Pfizer's and Pharmacia's Vioxx) may increase the risk...that patients treated with Celebrex or Vioxx were more likely to suffer...cardiovascular problems after taking Celebrex, Vioxx or Wyeth-Ayerst's Londine...


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Two expensive pain relievers often prescribed when cheaper medicines would...: Newspaper article from: Pain & Central Nervous System Week July 1, 2002 700+ words
...Scripts, Inc. The drugs - Vioxx and Celebrex - are heralded for their ability...t included in the study. Vioxx and Celebrex were introduced in 1999...substantial: A month's supply of Celebrex or Vioxx costs about $80, while a month...

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Source: HighBeam Research, CELEBREX AND VIOXX: ARE THEY SAFER THAN THE OLDER ANTI- INFLAMMATORY...

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