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HRT proven effective for reducing bone fractures. (More Whi Data).
SAN ANTONIO -- Results from the Women's Health Initiative trial have definitively proven for the first time that hormone replacement therapy can cut the incidence of bone fractures in postmenopausal women.
Findings from earlier studies had shown that estrogen treatment raised the bone mineral density of postmenopausal women, and the results from a handful of small studies had hinted that the fracture rate was decreased. But it took the massive Women's Health Initiative (WHI), which enrolled more than 16,000 women, to clearly prove that fracture rates drop when postmenopausal women take estrogen, Dr. John A. Robbins said at the annual meeting of the American Society for Bone and Mineral Research.
The trial, done at 40 centers in the United States, made headlines last July when one arm of the study was stopped early because of an excess of cases of invasive breast cancer among women who took a daily dosage of 0.625 mg of conjugated equine estrogen and 2.5 mg of medroxyprogesterone, compared with the control group who received placebo.
Dr. Robbins, who said he doesn't have any financial ties to companies that market estrogen products, presented further details on ...
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Source: HighBeam Research, HRT proven effective for reducing bone fractures. (More Whi Data).